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T22453 |
Venlafaxine
|
Wy 45030 |
Serotonin Transporter
|
|
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia. |
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T21013 |
Clomipramine
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Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina |
5-HT Receptor
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Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su... |
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T0255 |
Clomipramine hydrochloride
|
Clomipramine HCl,Anafranil |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
,
GST
|
|
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth... |
|
T0472 |
Venlafaxine hydrochloride
|
Venlafaxine HCl,Wy 45030 hydrochloride |
5-HT Receptor
,
Serotonin Transporter
|
|
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT. |
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T21029 |
Norfluoxetine Hydrochloride
|
Norfluoxetine HCl |
Others
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Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug. |
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T1483 |
Citalopram hydrobromide
|
Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr |
5-HT Receptor
,
Serotonin Transporter
,
Autophagy
|
|
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system... |
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T3275 |
Nefazodone hydrochloride
|
Dutonin,MJ-13754-1,Serzone,BMY-13754-1,BMY-13754 |
5-HT Receptor
,
Adrenergic Receptor
|
|
Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder. |
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T68040 |
Cericlamine
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|
5-HT Receptor
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Cericlamine is a selective 5-hydroxytryptamine (5-HT) reuptake blocker with antidepressant activity. |
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T24444 |
Medifoxamine
|
LG 152,Medifoxamina,LG-152,LG152 |
Dopamine Receptor
,
Monoamine Oxidase
|
|
Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine preferentially inhibits dopamine reuptake. |
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T1279 |
Vilazodone
|
SB659746A,EMD 68843 |
5-HT Receptor
,
Serotonin Transporter
|
|
Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the reuptake of serotonin from... |
|
T0450 |
Fluoxetine
|
LY-110140 |
5-HT Receptor
,
Serotonin Transporter
,
MRP
,
Autophagy
|
|
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity. |
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T28809 |
SLV-310
|
SLV 310,SLV310 |
Dopamine Receptor
,
5-HT Receptor
|
|
SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and schizophrenia. |
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T60325 |
Viloxazine
|
Emovit,Viloxazin |
5-HT Receptor
,
Norepinephrine
|
|
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2... |
|
T6493 |
Escitalopram Oxalate
|
Cipralex,(S)-(+)Citalopram oxalate |
Others
,
5-HT Receptor
,
Serotonin Transporter
|
|
Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM. |
|
T2594 |
Dextromilnacipran
|
Levomilnacipran |
Serotonin Transporter
,
Norepinephrine
|
|
Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor. |
|
T2402 |
Tianeptine sodium salt
|
Tianeptine sodium |
5-HT Receptor
|
|
Tianeptine sodium salt is a selective serotonin reuptake enhancer (SSRE), used to treat major depressive episodes. |
|
T67956L |
Litoxetine HCl
|
litoxetine HCL(86811-09-8 Free base) |
5-HT Receptor
|
|
Litoxetine HCl is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor (SSRI) and mixed 5-hydroxytryptamine antagonist used in the treatment of urinary incontinence. Litoxetine HCl in the absence of antimuscarinic c... |
|
T6188 |
Desvenlafaxine succinate hydrate
|
O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,Desvenlafaxine Succinate |
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI). |
|
T1580 |
Desvenlafaxine
|
WY 45233 Succinate,O-Desmethylvenlafaxine |
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive age... |
|
T7061 |
Duloxetine
|
|
Serotonin Transporter
|
|
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder. |
|
T68910 |
Ifoxetine
|
|
|
|
Ifoxetine is a 5-HT reuptake inhibitor. |
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T30489 |
BMS 181101
|
BMS181101,BMS-181101 |
|
|
BMS-181101 is a novel antidepressant that has pharmacological characteristics as a serotonin reuptake inhibitor and a serotonin 5-HT receptor agonist. |
|
T13339 |
Wf-516
|
|
5-HT Receptor
|
|
Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant activity. |
|
T8443L |
MCI-225 hydrochloride hydrate
|
AA-10021,AA10021,MCI225,DDP-225,AA-10025,AA-10026 |
|
|
MCI-225 is a norepinephrine reuptake/5-HT3/5-HT reuptake inhibitor. MCI-225 could be effective in the treatment of senile dementia of the Alzheimer type, which is accompanied with both deficit in the BF-cortex cholinergi... |
|
T25110 |
AS1069562
|
AS-1069562,AS 1069562 |
|
|
AS1069562 is an inhibitor of serotonin (5-HT) and norepinephrine (NE) reuptake which acts by notably restoring reduced insulin-like growth factor 1 and fibroblast growth factor 2 mRNA levels in dorsal root ganglion and s... |
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T60508 |
(S)-Venlafaxine
|
|
|
|
(S)-Venlafaxine is the (S)-configuration of Venlafaxine which is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor with antidepressant activity [1]. |
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T73977 |
(S)-Dehydro Venlafaxine
|
|
|
|
(S)-Dehydro Venlafaxine is an inactive S-enantiomer of Dehydro Venlafaxine. Dehydro Venlafaxine is an impurity of Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a potent serotonin (5-HT)... |
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T60607 |
Dasotraline
|
|
|
|
Dasotraline is a triple reuptake inhibitor that blocks dopamine(DA), norepinephrine(NE), and serotonin [5-hydroxytryptamine (5-HT)] transporters with IC 50 values of 4, 6, and 11 nM, respectively. Dasotraline represents ... |
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T37167 |
Reduced Haloperidol
|
|
|
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Reduced haloperidol is an active metabolite of haloperidol . It is formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4... |
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T83888 |
(S)-5-hydroxy-6-methoxy Duloxetine maleate
|
|
|
|
(S)-5-hydroxy-6-methoxy Duloxetine, an active metabolite of the (S)-duloxetine, functions as a serotonin (5-HT) and norepinephrine reuptake inhibitor. Its formation occurs through the cytochrome P450 (CYP) isoforms CYP1A... |
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T70960 |
Maprotiline-d3 hydrochloride
|
|
|
|
Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selecti... |
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T36521 |
Alaproclate (hydrochloride)
|
|
|
|
Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s =... |
